i want to say don't give up . but giving up doesn't really work that easily. there are somethings that hurt you if you don't give up and there's something that hurts you if you give up. For example if your pursuit of finding a love partner is bringing you pain, then giving that up is good. but if you're thinking of giving up on life or happiness. then don't because that will hurt you. as a rule of thumb. use your values to judge the positive and negative things in your life. and then give up on the negative things and do all the positive things with more concentration.
I understand what you are saying, I really do. I'm probably older than you and have been dealing with this thought for a very long time. I know they say taking your own life is wrong but I really don't see any positivity coming my way, as a matter of fact, just when I think things are starting to look up, something comes along and stomps it back down and not always self doing.